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  • Cancer Vaccine That Mimics Lymph Node
    SubComdTaco writes "Harvard has announced their approach towards an implantable cancer vaccine (press release here). To anyone familiar with how the immune system works, this appears to be a synthetic lymph node, an intriguing bit of biomimicry. From the Science Daily article: 'A cancer vaccine carried into the body on a carefully engineered, fingernail-sized implant is the first to successfully eliminate tumors in mammals, scientists recently reported in the journal Science Translational Medicine. The new approach, pioneered by bioengineers and immunologists at Harvard University, uses plastic disks impregnated with tumor-specific antigens and implanted under the skin to reprogram the mammalian immune system to attack tumors. The new paper describes the use of such implants to eradicate melanoma tumors in mice. ... The slender implants... are 8.5 millimeters in diameter and made of an FDA-approved biodegradable polymer. Ninety percent air, the disks are highly permeable to immune cells and release cytokines, powerful recruiters of immune-system messengers called dendritic cells. These cells enter an implant's pores, where they are exposed to antigens specific to the type of tumor being targeted. The dendritic cells then report to nearby lymph nodes, where they direct the immune system's T cells to hunt down and kill tumor cells.'"

    Read more of this story at Slashdot.


  • Home Router For High-Speed Connection?
    soulprivate writes "My cable company has recently begun to offer Internet access plans with speeds over 30 Mbps (60, 80 and 100 Mbps). However my D-link router is unable to go beyond 30 Mbps if I use NAT; it reaches 60-70 Mbps only if NAT is disabled. Is there any recommendation for a brand/model of residential router that is able to get more than 70 Mbps with NAT enabled? I have been looking for benchmarks or comparisons, to no avail. Does anyone knows one? And/or what are your experiences at home?"

    Read more of this story at Slashdot.


  • Engaging With Climate Skeptics
    In the wake of the CRU "climategate" leak, reader Geoffrey.landis sends along a New York Times blog profile of Judith Curry, a climate scientist at Georgia Tech. "Curry — unlike many climate scientists — does not simply dismiss the arguments of 'climate skeptics,' but attempts to engage them in dialogue. She can, as well, be rather pointed in criticizing her colleagues, as in a post on the skeptic site climateaudit where she argues for greater transparency for climate data and calculations (mirrored here). In this post she makes a point that tribalism in science is the main culprit here —- that when scientists 'circle the wagons' to defend against what they perceive to be unfair (and unscientific) attacks, the result can be damaging to the actual science being defended. Is it still possible to conduct a dialogue, or is there no possible common ground?"

    Read more of this story at Slashdot.


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